The following data sets has been made accessible for others to use (see Files below).
Data set 0: Tutorial data
Data used in the tutorial.
Data set 1: "NFI-data"
Profile types: STR DNA
- 49 three-person mixtures (one replicates each, variety of degradation)
- 4 two-person mixtures (has four replicates each, non-degraded)
- 4 three-person mixtures (has four replicates each, non-degraded)
- 2 three-person mixtures (has four replicates each, very degraded)
- 33 reference profiles
System:
The STR DNA profiles were generated using the NGM kit (Life Technologies) with 29 cycles and a 9700 thermal cycler (Life Technologies). Amplification products were separated by capillary electrophoresis (CE) on a 3130xl Genetic Analyzer (Life Technologies) at 3 kV for 5 s. The results were analyzed with GeneMapper® ID-X Software v.1.1.1 (Applied Biosystems) using a marker specific stutter filter as described in Westen et.al. (2014)[1]. Alleles with peak heights below 50 relative fluorescence units (RFU) were removed.
Acknowledgement:
Professor Peter de Knijff from Leiden University Medical Center, The Netherlands, provided the profiles and made them accessible.
References:
[1] A. A. Westen, T. Kraaijenbrink, E. A. Robles de Medina, J. Harteveld, P. Willemse, S. B. Zuniga, K. J. van der Gaag, N. E.C. Weiler, J. Warnaar, M. Kayser, T. Sijen, and P. de Knijff. Comparing six commercial autosomal STR kits in a large Dutch population sample. Forensic Science International: Genetics, 10:55-63, 2014
Data set 2: ENFSI exercise 1 and 2
Part of learning material of EuroForMix. See youtube vidoes,
Data set 3: Robber sample
Data for publication Bleka and Gill (2015): Interpretation of a complex STR DNA profile using EuroForMix; Forensic Science International: Genetics Supplement Series 5 (2015) e405–e406.
Data set 4: SNP data
Data for publication Bleka et al. (2017): Open source software EuroForMix can be used to analyse complex SNP mixtures. Forensic Sci Int Genet. 2017 Nov;31:105-110
Data set 5: Real case data for CaseSolver
Data for publication Bleka et al. (2019): CaseSolver: An investigative open source expert system based on EuroForMix. Forensic Sci Int Genet. 2019 Jul;41:83-92
Data set 6: MPS STR data
Data for publication Bleka et al. (2020): An examination of STR nomenclatures, filters and models for MPS mixture interpretation;Forensic Sci Int Genet.,48: 102319, 2020
